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Lysyl oxidase promotes renal fibrosis via accelerating collagen cross‐link driving by β‐arrestin/ERK/STAT3 pathway

Lysyl oxidase (LOX) is a copper‐dependent monoamine oxidase whose primary function is the covalent cross‐linking of collagen in the extracellular matrix (ECM). Evidence has shown that LOX is associated with cancer and some fibrotic conditions. We recently found that serum LOX is a potential diagnost...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqin, Zhou, Wenqian, Niu, Yangyang, Zhu, Saiya, Zhang, Yingying, Li, Xiaogang, Yu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544652/
https://www.ncbi.nlm.nih.gov/pubmed/35792886
http://dx.doi.org/10.1096/fj.202200573R