d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?

BACKGROUND AND PURPOSE: Recent evidence links brain insulin resistance with neurodegenerative diseases, where hyperphosphorylated tau protein contributes to neuronal cell death. In the present study, we aimed to evaluate if d‐pinitol inositol, which acts as an insulin sensitizer, affects the phospho...

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Detalles Bibliográficos
Autores principales: Medina‐Vera, Dina, Navarro, Juan Antonio, Rivera, Patricia, Rosell‐Valle, Cristina, Gutiérrez‐Adán, Alfonso, Sanjuan, Carlos, López‐Gambero, Antonio Jesús, Tovar, Rubén, Suárez, Juan, Pavón, Francisco Javier, Baixeras, Elena, Decara, Juan, Rodríguez de Fonseca, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544772/
https://www.ncbi.nlm.nih.gov/pubmed/35760415
http://dx.doi.org/10.1111/bph.15907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544772/
https://www.ncbi.nlm.nih.gov/pubmed/35760415
http://dx.doi.org/10.1111/bph.15907

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