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d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?
BACKGROUND AND PURPOSE: Recent evidence links brain insulin resistance with neurodegenerative diseases, where hyperphosphorylated tau protein contributes to neuronal cell death. In the present study, we aimed to evaluate if d‐pinitol inositol, which acts as an insulin sensitizer, affects the phospho...
Autores principales: | Medina‐Vera, Dina, Navarro, Juan Antonio, Rivera, Patricia, Rosell‐Valle, Cristina, Gutiérrez‐Adán, Alfonso, Sanjuan, Carlos, López‐Gambero, Antonio Jesús, Tovar, Rubén, Suárez, Juan, Pavón, Francisco Javier, Baixeras, Elena, Decara, Juan, Rodríguez de Fonseca, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544772/ https://www.ncbi.nlm.nih.gov/pubmed/35760415 http://dx.doi.org/10.1111/bph.15907 |
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