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Polysorbate 80 and histidine quantitative analysis by NMR in the presence of virus‐like particles
Polysorbate‐80 (PS80) and histidine are common excipients in vaccine and therapeutic protein formulation. A simple quantitative NMR method to measure both PS80 and histidine in human papillomavirus (HPV) virus‐like particle (VLP) vaccine for aqueous and alum‐containing samples is described. The new...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544792/ https://www.ncbi.nlm.nih.gov/pubmed/35366009 http://dx.doi.org/10.1002/elps.202100189 |