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Polysorbate 80 and histidine quantitative analysis by NMR in the presence of virus‐like particles

Polysorbate‐80 (PS80) and histidine are common excipients in vaccine and therapeutic protein formulation. A simple quantitative NMR method to measure both PS80 and histidine in human papillomavirus (HPV) virus‐like particle (VLP) vaccine for aqueous and alum‐containing samples is described. The new...

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Detalles Bibliográficos
Autor principal: Rustandi, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544792/
https://www.ncbi.nlm.nih.gov/pubmed/35366009
http://dx.doi.org/10.1002/elps.202100189