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An alternative downstream translation start site in the non‐TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages

Toll‐like receptor (TLR) signaling relies on Toll/interleukin‐1 receptor homology (TIR) domain‐containing adaptor proteins that recruit downstream signaling molecules to generate tailored immune responses. In addition, the palmitoylated transmembrane adaptor protein family member Scimp acts as a non...

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Detalles Bibliográficos
Autores principales: Curson, James EB, Luo, Lin, Liu, Liping, Burgess, Belinda J, Bokil, Nilesh J, Wall, Adam A, Brdicka, Tomas, Kapetanovic, Ronan, Stow, Jennifer L, Sweet, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544816/
https://www.ncbi.nlm.nih.gov/pubmed/35201640
http://dx.doi.org/10.1111/imcb.12540