IgG Anti–Citrullinated Protein Antibody Variable Domain Glycosylation Increases Before the Onset of Rheumatoid Arthritis and Stabilizes Thereafter: A Cross‐Sectional Study Encompassing ~1,500 Samples

OBJECTIVE: The autoimmune response in rheumatoid arthritis (RA) is marked by the presence of anti–citrullinated protein antibodies (ACPAs). A notable feature of IgG ACPA is the abundant expression of N‐linked glycans in the variable domain. However, the presence of ACPA variable domain glycosylation...

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Detalles Bibliográficos
Autores principales: Kissel, Theresa, Hafkenscheid, Lise, Wesemael, Tineke J., Tamai, Mami, Kawashiri, Shin‐ya, Kawakami, Atsushi, El‐Gabalawy, Hani S., van Schaardenburg, Dirkjan, Rantapää‐Dahlqvist, Solbritt, Wuhrer, Manfred, van der Helm‐van Mil, Annette H. M., Allaart, Cornelia F., van der Woude, Diane, Scherer, Hans U., Toes, Rene E. M., Huizinga, Tom W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544857/
https://www.ncbi.nlm.nih.gov/pubmed/35188715
http://dx.doi.org/10.1002/art.42098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544857/
https://www.ncbi.nlm.nih.gov/pubmed/35188715
http://dx.doi.org/10.1002/art.42098

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