Application of metabolite set enrichment analysis on untargeted metabolomics data prioritises relevant pathways and detects novel biomarkers for inherited metabolic disorders

Untargeted metabolomics (UM) allows for the simultaneous measurement of hundreds of metabolites in a single analytical run. The sheer amount of data generated in UM hampers its use in patient diagnostics because manual interpretation of all features is not feasible. Here, we describe the application...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoegen, Brechtje, Hampstead, Juliet E., Engelke, Udo F.H., Kulkarni, Purva, Wevers, Ron A., Brunner, Han G., Coene, Karlien L. M., Gilissen, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544878/
https://www.ncbi.nlm.nih.gov/pubmed/35546254
http://dx.doi.org/10.1002/jimd.12522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544878/
https://www.ncbi.nlm.nih.gov/pubmed/35546254
http://dx.doi.org/10.1002/jimd.12522

Ejemplares similares