Cargando…

Flow cytometry‐based high‐throughput RNAi screening for miRNAs regulating MHC class II HLA‐DR surface expression

HLA‐DR isotype is a MHC‐II cell‐surface receptor found on APCs and plays a key role in initiating immune responses. In severely immunocompromised patients with conditions like sepsis, the number of HLA‐DR molecules expressed on leukocytes is considered to correlate with infectious complications and...

Descripción completa

Detalles Bibliográficos
Autores principales: Houseman, Maja, Huang, Melody Ying‐Yu, Huber, Markus, Staiger, Matthias, Zhang, Lan, Hoffmann, Anneliese, Lippuner, Christoph, Stüber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544904/
https://www.ncbi.nlm.nih.gov/pubmed/35612261
http://dx.doi.org/10.1002/eji.202149735