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Flow cytometry‐based high‐throughput RNAi screening for miRNAs regulating MHC class II HLA‐DR surface expression
HLA‐DR isotype is a MHC‐II cell‐surface receptor found on APCs and plays a key role in initiating immune responses. In severely immunocompromised patients with conditions like sepsis, the number of HLA‐DR molecules expressed on leukocytes is considered to correlate with infectious complications and...
Autores principales: | Houseman, Maja, Huang, Melody Ying‐Yu, Huber, Markus, Staiger, Matthias, Zhang, Lan, Hoffmann, Anneliese, Lippuner, Christoph, Stüber, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544904/ https://www.ncbi.nlm.nih.gov/pubmed/35612261 http://dx.doi.org/10.1002/eji.202149735 |
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