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Interleukin‐4 receptor alpha signaling regulates monocyte homeostasis

Interleukin‐4 (IL‐4) and its receptors (IL‐4R) promote the proliferation and polarization of macrophages. However, it is unknown if IL‐4R also influences monocyte homeostasis and if steady state IL‐4 levels are sufficient to affect monocytes. Employing full IL‐4 receptor alpha knockout mice (IL‐4Rα(...

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Detalles Bibliográficos
Autores principales: Haider, Patrick, Kral‐Pointner, Julia B., Salzmann, Manuel, Moik, Florian, Bleichert, Sonja, Schrottmaier, Waltraud C., Kaun, Christoph, Brekalo, Mira, Fischer, Michael B., Speidl, Walter S., Hengstenberg, Christian, Podesser, Bruno K., Huber, Kurt, Pabinger, Ingrid, Knapp, Sylvia, Brombacher, Frank, Brostjan, Christine, Ay, Cihan, Wojta, Johann, Hohensinner, Philipp J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544925/
https://www.ncbi.nlm.nih.gov/pubmed/36063138
http://dx.doi.org/10.1096/fj.202101672RR