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A Randomized First‐in‐Human Study With UB‐312, a UBITh® α‐Synuclein Peptide Vaccine

BACKGROUND: α‐Synuclein (αSyn) is believed to play a central role in Parkinson's disease (PD) neuropathology and is considered a target for disease modification. UB‐312 is a synthetic αSyn peptide conjugated to a T helper peptide and is expected to induce antibodies specifically against oligome...

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Detalles Bibliográficos
Autores principales: Yu, Hui Jing, Thijssen, Eva, van Brummelen, Emilie, van der Plas, Johan L., Radanovic, Igor, Moerland, Matthijs, Hsieh, Eric, Groeneveld, Geert Jan, Dodart, Jean‐Cosme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545051/
https://www.ncbi.nlm.nih.gov/pubmed/35426173
http://dx.doi.org/10.1002/mds.29016