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Direct Enantioselective Addition of Alkynes to Imines by a Highly Efficient Palladacycle Catalyst

Enantiopure propargylic amines are highly valuable synthetic building blocks. Much effort has been devoted to develop methods for their preparation. The arguably most important strategy is the 1,2‐addition of alkynes to imines. Despite remarkable progress, the known methods using Zn and Cu catalysts...

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Detalles Bibliográficos
Autores principales: Pfeffer, Camilla, Probst, Patrick, Wannenmacher, Nick, Frey, Wolfgang, Peters, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545068/
https://www.ncbi.nlm.nih.gov/pubmed/35701311
http://dx.doi.org/10.1002/anie.202206835