Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation

To control infections phagocytes can directly kill invading microbes. Macrophage‐expressed gene 1 (Mpeg1), a pore‐forming protein sometimes known as perforin‐2, is reported to be essential for bacterial killing following phagocytosis. Mice homozygous for the mutant allele Mpeg1 ( tm1Pod ) succumb to...

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Detalles Bibliográficos
Autores principales: Ebrahimnezhaddarzi, Salimeh, Bird, Catherina H, Allison, Cody C, Tuipulotu, Daniel E, Kostoulias, Xenia, Macri, Christophe, Stutz, Michael D, Abraham, Gilu, Kaiserman, Dion, Pang, Siew Siew, Man, Si Ming, Mintern, Justine D, Naderer, Thomas, Peleg, Anton Y, Pellegrini, Marc, Whisstock, James C, Bird, Phillip I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545170/
https://www.ncbi.nlm.nih.gov/pubmed/35471730
http://dx.doi.org/10.1111/imcb.12554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545170/
https://www.ncbi.nlm.nih.gov/pubmed/35471730
http://dx.doi.org/10.1111/imcb.12554

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