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Vitamin B6 rescues insulin resistance and glucose‐induced DNA damage caused by reduced activity of Drosophila PI3K

The insulin signaling pathway controls cell growth and metabolism, thus its deregulation is associated with both cancer and diabetes. Phosphatidylinositol 3‐kinase (PI3K) contributes to the cascade of phosphorylation events occurring in the insulin pathway by activating the protein kinase B (PKB/AKT...

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Detalles Bibliográficos
Autores principales: Mascolo, Elisa, Liguori, Francesco, Merigliano, Chiara, Schiano, Ludovica, Gnocchini, Eleonora, Pilesi, Eleonora, Volonté, Cinzia, Di Salvo, Martino L., Contestabile, Roberto, Tramonti, Angela, Vernì, Fiammetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545242/
https://www.ncbi.nlm.nih.gov/pubmed/35678366
http://dx.doi.org/10.1002/jcp.30812