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Structure‐guided engineering of key amino acids in UGT85B1 controlling substrate and stereo‐specificity in aromatic cyanogenic glucoside biosynthesis

Cyanogenic glucosides are important defense molecules in plants with useful biological activities in animals. Their last biosynthetic step consists of a glycosylation reaction that confers stability and increases structural diversity and is catalyzed by the UDP‐dependent glycosyltransferases (UGTs)...

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Detalles Bibliográficos
Autores principales: Del Giudice, Rita, Putkaradze, Natalia, dos Santos, Bruna Marques, Hansen, Cecilie Cetti, Crocoll, Christoph, Motawia, Mohammed Saddik, Fredslund, Folmer, Laursen, Tomas, Welner, Ditte Hededam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545476/
https://www.ncbi.nlm.nih.gov/pubmed/35819080
http://dx.doi.org/10.1111/tpj.15904