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Structure‐guided engineering of key amino acids in UGT85B1 controlling substrate and stereo‐specificity in aromatic cyanogenic glucoside biosynthesis
Cyanogenic glucosides are important defense molecules in plants with useful biological activities in animals. Their last biosynthetic step consists of a glycosylation reaction that confers stability and increases structural diversity and is catalyzed by the UDP‐dependent glycosyltransferases (UGTs)...
Autores principales: | Del Giudice, Rita, Putkaradze, Natalia, dos Santos, Bruna Marques, Hansen, Cecilie Cetti, Crocoll, Christoph, Motawia, Mohammed Saddik, Fredslund, Folmer, Laursen, Tomas, Welner, Ditte Hededam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545476/ https://www.ncbi.nlm.nih.gov/pubmed/35819080 http://dx.doi.org/10.1111/tpj.15904 |
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