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Late‐Stage Functionalisation of Peptides on the Solid Phase by an Iodination‐Substitution Approach

The functionalisation of peptides at a late synthesis stage holds great potential, for example, for the synthesis of peptide pharmaceuticals, fluorescent biosensors or peptidomimetics. Here we describe an on‐resin iodination‐substitution reaction sequence on homoserine that is also suitable for pept...

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Detalles Bibliográficos
Autores principales: Werner, Marius, Pampel, Julius, Pham, Truc Lam, Thomas, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545490/
https://www.ncbi.nlm.nih.gov/pubmed/35700354
http://dx.doi.org/10.1002/chem.202201339