Hemocyte differentiation to the megacyte lineage enhances mosquito immunity against Plasmodium

Activation of Toll signaling in Anopheles gambiae by silencing Cactus, a suppressor of this pathway, enhances local release of hemocyte-derived microvesicles (HdMv), promoting activation of the mosquito complement-like system, which eliminates Plasmodium ookinetes. We uncovered the mechanism of this...

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Detalles Bibliográficos
Autores principales: Barletta, Ana Beatriz F, Saha, Banhisikha, Trisnadi, Nathanie, Talyuli, Octavio AC, Raddi, Gianmarco, Barillas-Mury, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545522/
https://www.ncbi.nlm.nih.gov/pubmed/36052991
http://dx.doi.org/10.7554/eLife.81116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545522/
https://www.ncbi.nlm.nih.gov/pubmed/36052991
http://dx.doi.org/10.7554/eLife.81116

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