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Hemocyte differentiation to the megacyte lineage enhances mosquito immunity against Plasmodium
Activation of Toll signaling in Anopheles gambiae by silencing Cactus, a suppressor of this pathway, enhances local release of hemocyte-derived microvesicles (HdMv), promoting activation of the mosquito complement-like system, which eliminates Plasmodium ookinetes. We uncovered the mechanism of this...
Autores principales: | Barletta, Ana Beatriz F, Saha, Banhisikha, Trisnadi, Nathanie, Talyuli, Octavio AC, Raddi, Gianmarco, Barillas-Mury, Carolina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545522/ https://www.ncbi.nlm.nih.gov/pubmed/36052991 http://dx.doi.org/10.7554/eLife.81116 |
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