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Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

The type VI secretion system (T6SS) is used by bacteria to deliver toxic effectors directly into target cells. Most T6SSs mediate antibacterial activities, whereas the potential anti-eukaryotic role of T6SS remains understudied. Here, we found a Vibrio T6SS that delivers two novel effectors into mam...

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Detalles Bibliográficos
Autores principales: Cohen, Hadar, Baram, Noam, Fridman, Chaya Mushka, Edry-Botzer, Liat, Salomon, Dor, Gerlic, Motti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545535/
https://www.ncbi.nlm.nih.gov/pubmed/36155655
http://dx.doi.org/10.7554/eLife.82766