Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists

OBJECTIVE: To characterize the effects of blocking calcitonin gene‐related peptide (CGRP) activity in a mouse model of gastrointestinal transport. BACKGROUND: Migraine management using CGRP modulating therapies can cause constipation of varying frequency and severity. This variation might be due to...

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Detalles Bibliográficos
Autores principales: Johnson, Kirk W., Li, Xia, Huang, Xiaofang, Heinz, Beverly A., Yu, Jianliang, Li, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Submissions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545683/
https://www.ncbi.nlm.nih.gov/pubmed/35822594
http://dx.doi.org/10.1111/head.14336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545683/
https://www.ncbi.nlm.nih.gov/pubmed/35822594
http://dx.doi.org/10.1111/head.14336

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