PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice

Rheumatoid arthritis (RA) is associated with HLA‐DRB1 alleles expressing the "shared epitope." RA is usually preceded by the emergence of anti‐citrullinated protein autoantibodies (ACPAs). ACPAs recognize citrulline residues on numerous proteins. Conversion of arginine into citrulline is p...

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Detalles Bibliográficos
Autores principales: Hemon, Marie F., Lambert, Nathalie C., Roudier, Jean, Auger, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Molecular immunology and signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545684/
https://www.ncbi.nlm.nih.gov/pubmed/35712879
http://dx.doi.org/10.1002/eji.202249889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545684/
https://www.ncbi.nlm.nih.gov/pubmed/35712879
http://dx.doi.org/10.1002/eji.202249889

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