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Growth of the airway smooth muscle layer from late gestation to childhood is mediated initially by hypertrophy and subsequently hyperplasia

BACKGROUND AND OBJECTIVE: The airway smooth muscle (ASM) layer thickens during development. Identifying the mechanism(s) for normal structural maturation of the ASM reveals pathways susceptible to disease processes. This study characterized thickening of the ASM layer from foetal life to childhood a...

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Detalles Bibliográficos
Autores principales: Wang, Kimberley C. W., Donovan, Graham M., Saglani, Sejal, Mauad, Thais, James, Alan L., Elliot, John G., Noble, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545757/
https://www.ncbi.nlm.nih.gov/pubmed/35266251
http://dx.doi.org/10.1111/resp.14240