Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts

BACKGROUND: Previous studies suggest that polygenic risk scores (PRSs) may improve melanoma risk stratification. However, there has been limited independent validation of PRS‐based risk prediction, particularly assessment of calibration (comparing predicted to observed risks). OBJECTIVES: To evaluat...

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Detalles Bibliográficos
Autores principales: Steinberg, Julia, Iles, Mark M., Lee, Jin Yee, Wang, Xiaochuan, Law, Matthew H., Smit, Amelia K., Nguyen‐Dumont, Tu, Giles, Graham G., Southey, Melissa C., Milne, Roger L., Mann, Graham J., Bishop, D. Timothy, MacInnis, Robert J., Cust, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545863/
https://www.ncbi.nlm.nih.gov/pubmed/34921685
http://dx.doi.org/10.1111/bjd.20956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545863/
https://www.ncbi.nlm.nih.gov/pubmed/34921685
http://dx.doi.org/10.1111/bjd.20956

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