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Pathological complete response in MMR-deficient/MSI-high and KRAS-mutant patient with locally advanced rectal cancer after neoadjuvant chemoradiation with immunotherapy: A case report

To date, preoperative chemoradiation (CRT) is the standard of care for patients with locally advanced rectal cancer (LARC) regardless of status of mismatch repair. Immunotherapy showed promising results in the neoadjuvant treatment trials in patients with mismatch repair-deficient (dMMR) or high mic...

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Detalles Bibliográficos
Autores principales: Zhang, Mai, Yang, Hua, Chen, Ling, Du, Kunli, Zhao, Lina, Wei, Lichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545900/
https://www.ncbi.nlm.nih.gov/pubmed/36212424
http://dx.doi.org/10.3389/fonc.2022.926480