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Nicotinamide pathways as the root cause of sepsis – an evolutionary perspective on macrophage energetic shifts

Divergent pathways of macrophage metabolism occur during infection, notably switching between oxidative phosphorylation and aerobic glycolysis (Warburg‐like metabolism). Concurrently, macrophages shift between alternate and classical activation. A key enzyme upregulated in alternatively activated ma...

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Detalles Bibliográficos
Autores principales: Suchard, Melinda S., Savulescu, Dana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9545938/
https://www.ncbi.nlm.nih.gov/pubmed/33686748
http://dx.doi.org/10.1111/febs.15807