Absorption, metabolism and excretion of opicapone in human healthy volunteers

AIMS: The absorption, metabolism and excretion of opicapone (2,5‐dichloro‐3‐(5‐[3,4‐dihydroxy‐5‐nitrophenyl]‐1,2,4‐oxadiazol‐3‐yl)‐4,6‐dimethylpyridine 1‐oxide), a selective catechol‐O‐methyltransferase inhibitor, were investigated. METHODS: Plasma, urine and faeces were collected from healthy male...

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Detalles Bibliográficos
Autores principales: Loureiro, Ana I., Rocha, Francisco, Santos, Ana T., Singh, Nand, Bonifácio, Maria João, Pinto, Rui, Kiss, Laszlo E., Soares‐da‐Silva, Patrício
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546099/
https://www.ncbi.nlm.nih.gov/pubmed/35508762
http://dx.doi.org/10.1111/bcp.15383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546099/
https://www.ncbi.nlm.nih.gov/pubmed/35508762
http://dx.doi.org/10.1111/bcp.15383

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