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Spatial transcriptome of a germinal center plasmablastic burst hints at MYD88/CD79B mutants‐enriched diffuse large B‐cell lymphomas

The GC reaction results in the selection of B cells acquiring effector Ig secreting ability by progressing toward plasmablastic differentiation. This transition is associated with exclusion from the GC microenvironment. The aberrant expansion of plasmablastic elements within the GC fringes configure...

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Detalles Bibliográficos
Autores principales: L'Imperio, Vincenzo, Morello, Gaia, Vegliante, Maria Carmela, Cancila, Valeria, Bertolazzi, Giorgio, Mazzara, Saveria, Belmonte, Beatrice, Mangogna, Alessandro, Balzarini, Piera, Corral, Lilia, Lopez, Gianluca, Di Napoli, Arianna, Facchetti, Fabio, Pagni, Fabio, Tripodo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546146/
https://www.ncbi.nlm.nih.gov/pubmed/35554927
http://dx.doi.org/10.1002/eji.202149746