Delineating selective vulnerability of inhibitory interneurons in Alpers' syndrome

AIMS: Alpers' syndrome is a severe neurodegenerative disease typically caused by bi‐allelic variants in the mitochondrial DNA (mtDNA) polymerase gene, POLG, leading to mtDNA depletion. Intractable epilepsy, often with an occipital focus, and extensive neurodegeneration are prominent features of...

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Detalles Bibliográficos
Autores principales: Smith, Laura A., Erskine, Daniel, Blain, Alasdair, Taylor, Robert W., McFarland, Robert, Lax, Nichola Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546160/
https://www.ncbi.nlm.nih.gov/pubmed/35790454
http://dx.doi.org/10.1111/nan.12833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546160/
https://www.ncbi.nlm.nih.gov/pubmed/35790454
http://dx.doi.org/10.1111/nan.12833

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