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A proteomics approach to decipher a sticky CHO situation

Chinese hamster ovary (CHO) cells serve as protein therapeutics workhorses, so it is useful to understand what intrinsic properties make certain host cell lines and clones preferable for scale up and production of target proteins. In this study, two CHO host cell lines (H1, H2), and their respective...

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Detalles Bibliográficos
Autores principales: Kumar, Swetha, Kumar, Amit, Huhn, Steven, DeVine, Lauren, Cole, Robert, Du, Zhimei, Betenbaugh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546176/
https://www.ncbi.nlm.nih.gov/pubmed/35470426
http://dx.doi.org/10.1002/bit.28108