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Polymorphic differences within HLA‐C alleles contribute to alternatively spliced transcripts lacking exon 5

The HLA genes are amongst the most polymorphic in the human genome. Alternative splicing could add an extra layer of complexity, but has not been studied extensively. Here, we applied an RNA based approach to study the influence of allele polymorphism on alternative splicing of HLA‐C in peripheral b...

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Detalles Bibliográficos
Autores principales: Ehlers, Femke A. I., Olieslagers, Timo I., Groeneweg, Mathijs, Bos, Gerard M. J., Tilanus, Marcel G. J., Voorter, Christina E. M., Wieten, Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546215/
https://www.ncbi.nlm.nih.gov/pubmed/35650170
http://dx.doi.org/10.1111/tan.14695