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A‐to‐I RNA editing of Filamin A regulates cellular adhesion, migration and mechanical properties

A‐to‐I RNA editing by ADARs is an abundant epitranscriptomic RNA‐modification in metazoa. In mammals, Flna pre‐mRNA harbours a single conserved A‐to‐I RNA editing site that introduces a Q‐to‐R amino acid change in Ig repeat 22 of the encoded protein. Previously, we showed that FLNA editing regulates...

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Detalles Bibliográficos
Autores principales: Jain, Mamta, Weber, Andreas, Maly, Kathrin, Manjaly, Greeshma, Deek, Joanna, Tsvyetkova, Olena, Stulić, Maja, Toca‐Herrera, José L., Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546289/
https://www.ncbi.nlm.nih.gov/pubmed/35124883
http://dx.doi.org/10.1111/febs.16391