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A‐to‐I RNA editing of Filamin A regulates cellular adhesion, migration and mechanical properties
A‐to‐I RNA editing by ADARs is an abundant epitranscriptomic RNA‐modification in metazoa. In mammals, Flna pre‐mRNA harbours a single conserved A‐to‐I RNA editing site that introduces a Q‐to‐R amino acid change in Ig repeat 22 of the encoded protein. Previously, we showed that FLNA editing regulates...
Autores principales: | Jain, Mamta, Weber, Andreas, Maly, Kathrin, Manjaly, Greeshma, Deek, Joanna, Tsvyetkova, Olena, Stulić, Maja, Toca‐Herrera, José L., Jantsch, Michael F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546289/ https://www.ncbi.nlm.nih.gov/pubmed/35124883 http://dx.doi.org/10.1111/febs.16391 |
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