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Live‐Cell Imaging of Sterculic Acid—a Naturally Occurring 1,2‐Cyclopropene Fatty Acid—by Bioorthogonal Reaction with Turn‐On Tetrazine‐Fluorophore Conjugates

In the field of lipid research, bioorthogonal chemistry has made the study of lipid uptake and processing in living systems possible, whilst minimising biological properties arising from detectable pendant groups. To allow the study of unsaturated free fatty acids in live cells, we here report the u...

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Detalles Bibliográficos
Autores principales: Bertheussen, Kristine, van de Plassche, Merel, Bakkum, Thomas, Gagestein, Berend, Ttofi, Iakovia, Sarris, Alexi J. C., Overkleeft, Herman S., van der Stelt, Mario, van Kasteren, Sander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546306/
https://www.ncbi.nlm.nih.gov/pubmed/35838324
http://dx.doi.org/10.1002/anie.202207640