Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes

Inadequate β‐cell mass is essential for the pathogenesis of type 2 diabetes (T2D). Previous report showed that an immunomodulator FTY720, a sphingosine 1‐phosphate (S1P) receptor modulator, sustainably normalized hyperglycemia by stimulating β‐cell in vivo regeneration in db/db mice. We further exam...

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Detalles Bibliográficos
Autores principales: Wang, Yixin (Jim), Wang, Xiaoli, An, Annie, Zang, Mingfa, Xu, Ling, Gong, Kefeng, Song, Weihua, Li, Qing, Lu, Xiaojun, Xiao, Yong‐Fu, Yu, Guoliang, Ma, Zhongmin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546369/
https://www.ncbi.nlm.nih.gov/pubmed/35064580
http://dx.doi.org/10.1111/fcp.12760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546369/
https://www.ncbi.nlm.nih.gov/pubmed/35064580
http://dx.doi.org/10.1111/fcp.12760

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