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Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes
Inadequate β‐cell mass is essential for the pathogenesis of type 2 diabetes (T2D). Previous report showed that an immunomodulator FTY720, a sphingosine 1‐phosphate (S1P) receptor modulator, sustainably normalized hyperglycemia by stimulating β‐cell in vivo regeneration in db/db mice. We further exam...
Autores principales: | Wang, Yixin (Jim), Wang, Xiaoli, An, Annie, Zang, Mingfa, Xu, Ling, Gong, Kefeng, Song, Weihua, Li, Qing, Lu, Xiaojun, Xiao, Yong‐Fu, Yu, Guoliang, Ma, Zhongmin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546369/ https://www.ncbi.nlm.nih.gov/pubmed/35064580 http://dx.doi.org/10.1111/fcp.12760 |
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