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Farnesoid X receptor contributes to oleanolic acid‐induced cholestatic liver injury in mice

Farnesoid X receptor (FXR) is a nuclear receptor involved in the metabolism of bile acid. However, the molecular signaling of FXR in bile acid homeostasis in cholestatic drug‐induced liver injury remains unclear. Oleanolic acid (OA), a natural triterpenoid, has been reported to produce evident chole...

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Detalles Bibliográficos
Autores principales: Feng, Hong, Hu, Yan, Zhou, Shaoyu, Lu, Yuanfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546401/
https://www.ncbi.nlm.nih.gov/pubmed/35128688
http://dx.doi.org/10.1002/jat.4298