Cargando…
Farnesoid X receptor contributes to oleanolic acid‐induced cholestatic liver injury in mice
Farnesoid X receptor (FXR) is a nuclear receptor involved in the metabolism of bile acid. However, the molecular signaling of FXR in bile acid homeostasis in cholestatic drug‐induced liver injury remains unclear. Oleanolic acid (OA), a natural triterpenoid, has been reported to produce evident chole...
Autores principales: | Feng, Hong, Hu, Yan, Zhou, Shaoyu, Lu, Yuanfu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546401/ https://www.ncbi.nlm.nih.gov/pubmed/35128688 http://dx.doi.org/10.1002/jat.4298 |
Ejemplares similares
-
Repeated Oral Administration of Oleanolic Acid Produces Cholestatic Liver Injury in Mice
por: Lu, Yuan-Fu, et al.
Publicado: (2013) -
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH
por: Xu, Jun, et al.
Publicado: (2023) -
Role of farnesoid X receptor and bile acids in alcoholic liver disease
por: Manley, Sharon, et al.
Publicado: (2015) -
Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration
por: Li, Guodong, et al.
Publicado: (2015) -
Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype
por: Abu-Hayyeh, Shadi, et al.
Publicado: (2013)