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Investigating key factors underlying neurodegeneration linked to alpha‐synuclein spread

AIMS: It has long been considered that accumulation of pathological alpha‐synuclein (aSyn) leads to synaptic/neuronal loss which then results in behavioural and cognitive dysfunction. To investigate this claim, we investigated effects downstream of aSyn preformed fibrils (PFFs) and 6‐hydroxydopamine...

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Detalles Bibliográficos
Autores principales: Pang, Cindy C. C., Sørensen, Maja H., Lee, Krit, Luk, Kelvin C., Trojanowski, John Q., Lee, Virginia M. Y., Noble, Wendy, Chang, Raymond C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546483/
https://www.ncbi.nlm.nih.gov/pubmed/35727707
http://dx.doi.org/10.1111/nan.12829