Cargando…
The mismatch recognition protein MutSα promotes nascent strand degradation at stalled replication forks
Mismatch repair (MMR) is a replication-coupled DNA repair mechanism and plays multiple roles at the replication fork. The well-established MMR functions include correcting misincorporated nucleotides that have escaped the proofreading activity of DNA polymerases, recognizing nonmismatched DNA adduct...
Autores principales: | Zhang, Junqiu, Zhao, Xin, Liu, Lu, Li, Hao-Dong, Gu, Liya, Castrillon, Diego H., Li, Guo-Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546528/ https://www.ncbi.nlm.nih.gov/pubmed/36161943 http://dx.doi.org/10.1073/pnas.2201738119 |
Ejemplares similares
-
Actin nucleators safeguard replication forks by limiting nascent strand degradation
por: Nieminuszczy, Jadwiga, et al.
Publicado: (2023) -
Actin nucleators safeguard replication forks by limiting nascent strand degradation
por: Nieminuszczy, Jadwiga, et al.
Publicado: (2023) -
Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
por: Somyajit, Kumar, et al.
Publicado: (2015) -
Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
por: Somyajit, Kumar, et al.
Publicado: (2020) -
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
por: Malacaria, Eva, et al.
Publicado: (2019)