Cargando…

Quantitative prediction and measurement of Piezo's membrane footprint

Piezo proteins are mechanosensitive ion channels that can locally curve the membrane into a dome shape [Y. R. Guo, R. MacKinnon, eLife 6, e33660 (2017)]. The curved shape of the Piezo dome is expected to deform the surrounding lipid bilayer membrane into a membrane footprint, which may serve to ampl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haselwandter, Christoph A., Guo, Yusong R., Fu, Ziao, MacKinnon, Roderick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Physical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546538/ https://www.ncbi.nlm.nih.gov/pubmed/36166475 http://dx.doi.org/10.1073/pnas.2208027119

Ejemplares similares

Piezo’s membrane footprint and its contribution to mechanosensitivity
por: Haselwandter, Christoph A, et al.
Publicado: (2018)

Elastic properties and shape of the Piezo dome underlying its mechanosensory function
por: Haselwandter, Christoph A., et al.
Publicado: (2022)

Piezo1 as a force-through-membrane sensor in red blood cells
por: Vaisey, George, et al.
Publicado: (2022)

Structure-based membrane dome mechanism for Piezo mechanosensitivity
por: Guo, Yusong R, et al.
Publicado: (2017)

Membrane protein isolation and structure determination in cell-derived membrane vesicles
por: Tao, Xiao, et al.
Publicado: (2023)

Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on the membrane surface
por: Falzone, Maria E., et al.
Publicado: (2023)

The membrane electric field regulates the PIP(2)-binding site to gate the KCNQ1 channel
por: Mandala, Venkata Shiva, et al.
Publicado: (2023)

Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells
por: del Mármol, Josefina Inés, et al.
Publicado: (2018)

Yoda1’s energetic footprint on Piezo1 channels and its modulation by voltage and temperature
por: Wijerathne, Tharaka D., et al.
Publicado: (2022)

Voltage-sensor movements in the Eag Kv channel under an applied electric field
por: Mandala, Venkata Shiva, et al.
Publicado: (2022)

Freestanding lipid bilayer tensiometer for the study of mechanosensitive ion channels
por: Pérez-Mitta, Gonzalo, et al.
Publicado: (2023)

The mechanism of Gα(q) regulation of PLCβ3-catalyzed PIP2 hydrolysis
por: Falzone, Maria E., et al.
Publicado: (2023)

Correlation between structure and function in phosphatidylinositol lipid–dependent Kir2.2 gating
por: Zhang, Yuxi, et al.
Publicado: (2022)

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP(2) and Na(+) in a reconstituted system
por: Wang, Weiwei, et al.
Publicado: (2014)

X-ray structure of the mammalian GIRK2 – βγ G protein complex
por: Whorton, Matthew R., et al.
Publicado: (2013)

Regulation of Eag1 gating by its intracellular domains
por: Whicher, Jonathan R, et al.
Publicado: (2019)

The Barium Site in a Potassium Channel by X-Ray Crystallography
por: Jiang, Youxing, et al.
Publicado: (2000)

Structure of the CLC-1 chloride channel from Homo sapiens
por: Park, Eunyong, et al.
Publicado: (2018)

Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology
por: Tao, Xiao, et al.
Publicado: (2019)

Molecular structures of the human Slo1 K(+) channel in complex with β4
por: Tao, Xiao, et al.
Publicado: (2019)

The legacy environmental footprints of manufactured capital
por: Wang, Ranran, et al.
Publicado: (2023)

The Role of Membrane-Mediated Interactions in the Assembly and Architecture of Chemoreceptor Lattices
por: Haselwandter, Christoph A., et al.
Publicado: (2014)

Isolation of a Single Carboxyl-Carboxylate Proton Binding Site in the Pore of a Cyclic Nucleotide–Gated Channel
por: Morrill, James A., et al.
Publicado: (1999)

Molecular basis of signaling specificity between GIRK channels and GPCRs
por: Touhara, Kouki K, et al.
Publicado: (2018)

Are We Really Getting Conservation So Badly Wrong?
por: MacKinnon, Kathy
Publicado: (2011)

Experimental physics at low temperatures: an introductory survey
por: MacKinnon, Lachlan
Publicado: (1966)

Interpreting Physics
por: MacKinnon, Edward
Publicado: (2012)

Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel
por: Lockless, Steve W, et al.
Publicado: (2007)

Two Separate Interfaces between the Voltage Sensor and Pore Are Required for the Function of Voltage-Dependent K(+) Channels
por: Lee, Seok-Yong, et al.
Publicado: (2009)

The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers
por: Touhara, Kouki K, et al.
Publicado: (2016)

Structure of a CLC chloride ion channel by cryo-electron microscopy
por: Park, Eunyong, et al.
Publicado: (2016)

Piezotronics and piezo-phototronics
por: Wang, Zhong Lin
Publicado: (2014)

Directed Supramolecular Organization of N-BAR Proteins through Regulation of H0 Membrane Immersion Depth
por: Kahraman, Osman, et al.
Publicado: (2018)

Architecture and Function of Mechanosensitive Membrane Protein Lattices
por: Kahraman, Osman, et al.
Publicado: (2016)

Phosphatidic acid modulation of Kv channel voltage sensor function
por: Hite, Richard K, et al.
Publicado: (2014)

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel
por: Banerjee, Anirban, et al.
Publicado: (2013)

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
por: Brohawn, Stephen G., et al.
Publicado: (2014)

Molecular structure of human KATP in complex with ATP and ADP
por: Lee, Kenneth Pak Kin, et al.
Publicado: (2017)

The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation
por: Zhu, Jiejun, et al.
Publicado: (2023)

Cryo-EM analysis of PIP(2) regulation in mammalian GIRK channels
por: Niu, Yiming, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sf9g4vbqjf5d30pe7c1c44fpn5