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Precise timing of ERK phosphorylation/dephosphorylation determines the outcome of trial repetition during long-term memory formation

Two-trial learning in Aplysia reveals nonlinear interactions between training trials: A single trial has no effect, but two precisely spaced trials induce long-term memory. Extracellularly regulated kinase (ERK) activity is essential for intertrial interactions, but the mechanism remains unresolved....

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Detalles Bibliográficos
Autores principales: Kukushkin, Nikolay V., Tabassum, Tasnim, Carew, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546540/
https://www.ncbi.nlm.nih.gov/pubmed/36161885
http://dx.doi.org/10.1073/pnas.2210478119