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Precise timing of ERK phosphorylation/dephosphorylation determines the outcome of trial repetition during long-term memory formation
Two-trial learning in Aplysia reveals nonlinear interactions between training trials: A single trial has no effect, but two precisely spaced trials induce long-term memory. Extracellularly regulated kinase (ERK) activity is essential for intertrial interactions, but the mechanism remains unresolved....
Autores principales: | Kukushkin, Nikolay V., Tabassum, Tasnim, Carew, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546540/ https://www.ncbi.nlm.nih.gov/pubmed/36161885 http://dx.doi.org/10.1073/pnas.2210478119 |
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