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Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease

Stem cell transplantation and genetic therapies offer potential cures for patients with sickle cell disease (SCD), but these options require advanced medical facilities and are expensive. Consequently, these treatments will not be available for many years to the majority of patients suffering from t...

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Detalles Bibliográficos
Autores principales: Metaferia, Belhu, Cellmer, Troy, Dunkelberger, Emily B., Li, Quan, Henry, Eric R., Hofrichter, James, Staton, Dwayne, Hsieh, Matthew M., Conrey, Anna K., Tisdale, John F., Chatterjee, Arnab K., Thein, Swee Lay, Eaton, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546543/
https://www.ncbi.nlm.nih.gov/pubmed/36161945
http://dx.doi.org/10.1073/pnas.2210779119