Combining CRISPR-Cas9 and brain imaging to study the link from genes to molecules to networks

Receptors, transporters, and ion channels are important targets for therapy development in neurological diseases, but their mechanistic role in pathogenesis is often poorly understood. Gene editing and in vivo imaging approaches will help to identify the molecular and functional role of these target...

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Detalles Bibliográficos
Autores principales: Marciano, Sabina, Ionescu, Tudor M., Saw, Ran Sing, Cheong, Rachel Y., Kirik, Deniz, Maurer, Andreas, Pichler, Bernd J., Herfert, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546570/
https://www.ncbi.nlm.nih.gov/pubmed/36161926
http://dx.doi.org/10.1073/pnas.2122552119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546570/
https://www.ncbi.nlm.nih.gov/pubmed/36161926
http://dx.doi.org/10.1073/pnas.2122552119

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