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Combining CRISPR-Cas9 and brain imaging to study the link from genes to molecules to networks
Receptors, transporters, and ion channels are important targets for therapy development in neurological diseases, but their mechanistic role in pathogenesis is often poorly understood. Gene editing and in vivo imaging approaches will help to identify the molecular and functional role of these target...
Autores principales: | Marciano, Sabina, Ionescu, Tudor M., Saw, Ran Sing, Cheong, Rachel Y., Kirik, Deniz, Maurer, Andreas, Pichler, Bernd J., Herfert, Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546570/ https://www.ncbi.nlm.nih.gov/pubmed/36161926 http://dx.doi.org/10.1073/pnas.2122552119 |
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