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Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly

Many icosahedral viruses assemble proteinaceous precursors called proheads or procapsids. Proheads are metastable structures that undergo a profound structural transition known as expansion that transforms an immature unexpanded head into a mature genome-packaging head. Bacteriophage T4 is a model v...

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Detalles Bibliográficos
Autores principales: Fang, Qianglin, Tang, Wei-Chun, Fokine, Andrei, Mahalingam, Marthandan, Shao, Qianqian, Rossmann, Michael G., Rao, Venigalla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546572/
https://www.ncbi.nlm.nih.gov/pubmed/36161892
http://dx.doi.org/10.1073/pnas.2203272119