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Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responses

Steroid hormones perform diverse biological functions in developing and adult animals. However, the mechanistic basis for their tissue specificity remains unclear. In Drosophila, the ecdysone steroid hormone is essential for coordinating developmental timing across physically separated tissues. Ecdy...

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Detalles Bibliográficos
Autores principales: Uyehara, Christopher M., Leatham-Jensen, Mary, McKay, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546573/
https://www.ncbi.nlm.nih.gov/pubmed/36161884
http://dx.doi.org/10.1073/pnas.2208935119