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Super-enhancers conserved within placental mammals maintain stem cell pluripotency

Despite pluripotent stem cells sharing key transcription factors, their maintenance involves distinct genetic inputs. Emerging evidence suggests that super-enhancers (SEs) can function as master regulatory hubs to control cell identity and pluripotency in humans and mice. However, whether pluripoten...

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Detalles Bibliográficos
Autores principales: Zhang, Juqing, Zhou, Yaqi, Yue, Wei, Zhu, Zhenshuo, Wu, Xiaolong, Yu, Shuai, Shen, Qiaoyan, Pan, Qin, Xu, Wenjing, Zhang, Rui, Wu, Xiaojie, Li, Xinmei, Li, Yayu, Li, Yunxiang, Wang, Yu, Peng, Sha, Zhang, Shiqiang, Lei, Anmin, Ding, Xinbao, Yang, Fan, Chen, Xingqi, Li, Na, Liao, Mingzhi, Wang, Wei, Hua, Jinlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546576/
https://www.ncbi.nlm.nih.gov/pubmed/36161929
http://dx.doi.org/10.1073/pnas.2204716119