Circadian clock controls rhythms in ketogenesis by interfering with PPARα transcriptional network

Ketone bodies are energy-rich metabolites and signaling molecules whose production is mainly regulated by diet. Caloric restriction (CR) is a dietary intervention that improves metabolism and extends longevity across the taxa. We found that CR induced high-amplitude daily rhythms in blood ketone bod...

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Detalles Bibliográficos
Autores principales: Mezhnina, Volha, Ebeigbe, Oghogho P., Velingkaar, Nikkhil, Poe, Allan, Sandlers, Yana, Kondratov, Roman V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546578/
https://www.ncbi.nlm.nih.gov/pubmed/36161962
http://dx.doi.org/10.1073/pnas.2205755119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546578/
https://www.ncbi.nlm.nih.gov/pubmed/36161962
http://dx.doi.org/10.1073/pnas.2205755119

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